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Deborah Ferrington, Ph.D.
Departments of Ophthalmology & Visual Neurosciences, Biochemistry, Molecular Biology and Biophysics
Office: (612) 624-8267
Lab: (612) 626-7640
Fax: (612) 626-7148
Department of Ophthalmology & Neurosciences
380 Lions Research Building
2001 6th Street SE
Minneapolis, MN 55455
Education and Training
Graduate School: University of Kansas
Honors and Awards
Invited Speaker, International Society of Eye Research, Montreal, Canada, 2010
Keynote Speaker, Midwest Eye Research Symposium, Iowa City, IA, 2010
Invited Speaker, Oxidative Stress and Disease Gordon Research Conference, Il Ciocco, Italy, 2009
Invited Speaker, International Society of Eye Research, Beijing, China, 2008
Invited Speaker, Biology of Aging Gordon Research Conference, Les Diables, Switzerland, 2007
Invited Symposium Speaker, Association for Research in Vision and Ophthalmology International Conference, Ft. Lauderdale, Florida, 2006-07
Fesler-Lampert Chair in Aging Research, Center on Aging, University of Minnesota, 2003-04
Published Articles for research on AMD:
Nordgaard CL, Karunadharma PP, Feng X, Olsen TW, Ferrington DA. (2008) Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 49: 2848-55.
Ethen CM, Hussong SA, Reilly C, Feng X, Olsen TW, Ferrington DA. (2007) Transformation of the proteasome with age-related macular degeneration. FEBS Lett. 581: 885-90.
Nordgaard, C.L., Berg, K.M, Kapphahn, R.J., Reilly, C., Feng, X., Olsen, T.W., Ferrington, D.A., (2006) Proteomics of the Retinal Pigment Epithelium Reveals Altered Protein Expression at Progressive Stages of Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 47: 815-22.
Ethen CM, Reilly C, Feng X, Olsen TW, Ferrington DA. (2006) The proteome of central and peripheral retina with progression of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 47: 2280-90.
Published Articles on Proteasome research:
Balog, E.M., Lockamy, E.L., Thomas, D.D., Ferrington, D.A., (2009) Site-specific methionine oxidation initiates calmodulin degradation by the 20S proteasome. Biochemistry, 48: 3005-16.
Ferrington, D.A., Hussong, S.A., Roehrich, H., Kapphahn, R.J., Kavanaugh, S.M., Heuss, N.D., Gregerson, D.S., (2008) Immunoproteasome Responds to Injury in the Retina and Brain. J Neurochem, 106:158-69.
Kapphahn, R.J., Bigelow, E.J., and Ferrington, D.A., (2007) Age-dependent Inhibition of Proteasome Chymotrypsin-like Activity in the Retina. Exp. Eye Res., 84(4): 646-54.
Louie, J.L., Kapphahn, R.J. and Ferrington, D.A., (2002) Proteasome Function and Protein Oxidation in the Aged Retina. Exp. Eye Res. 75: 271-84.
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